Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients

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Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients

OBJECTIVE Children with epilepsy often have reorganization of language networks and abnormal brain anatomy, making determination of language lateralization difficult. We characterized the proportion and distribution of language task activation in the cerebellum to determine the relationship to cerebral language lateralization. METHODS Forty-six pediatric epilepsy surgery candidates (aged 7-19...

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Presurgical Language Mapping in Patients With Intractable Epilepsy: A Review Study

Introduction: about 20% to 30% of patients with epilepsy are diagnosed with drug-resistant epilepsy and one third of these are candidates for epilepsy surgery. Surgical resection of the epileptogenic tissue is a well-established method for treating patients with intractable focal epilepsy. Determining language laterality and locality is an important part of a comprehensive epilepsy program befo...

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Cerebral dominance for language in cerebral palsy.

A test of cerebral dominance for language was administered to 51 cerebral palsied adults. The test consisted of dichotically presented words and in normal speaking adults had previously demonstrated very marked right ear superiority, interpreted as left cerebral dominance. The group of cerebral palsied subjects did not show the predicted right ear superiority. This finding may represent a chanc...

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Real-time functional mapping: potential tool for improving language outcome in pediatric epilepsy surgery.

Accurate language localization expands surgical treatment options for epilepsy patients and reduces the risk of postsurgery language deficits. Electrical cortical stimulation mapping (ESM) is considered to be the clinical gold standard for language localization. While ESM affords clinically valuable results, it can be poorly tolerated by children, requires active participation and compliance, c...

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ژورنال

عنوان ژورنال: NeuroImage: Clinical

سال: 2014

ISSN: 2213-1582

DOI: 10.1016/j.nicl.2014.06.016